Consistent with this notion, mechanical efficiency was augmented by short-term allopurinol in patients with dilated cardiomyopathy, despite the fact that such patients were administered standard heart failure regimens
For myocarditis and inflammatory cardiomyopathy, an etiologically driven treatment is today the best option beyond heart failure therapy
Accordingly, we hypothesized that XO inhibition with intracoronary allopurinol improves left ventricular efficiency in patients with idiopathic dilated Similarly, the use of allopurinol did not reduce the odds of recurrent ACS events at 2 years (OR: 0
Conclusions: Periprocedural use of allopurinol might be associated with a significant reduction in the odds of ACS and cardiovascular mortality in patients undergoing CABG
Accordingly, we hypothesized that XO inhibition with intracoronary allopurinol improves left ventricular efficiency in patients with idiopathic dilated cardiomyopathy
Hence the possibility that ALLO might limit norepinephrine (NE) injury
Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) following the disassociation with its repressor Keap1 under oxidative stress can maintain inner redox homeostasis and attenuate DCM with concomitant attenuation of
Modulation of catecholamine cardiomyopathy by allopurinol It has been suggested that cardiac injury by catecholamines may be the result of coronary constriction leading to ischemic damage
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Allopurinol (ALP) attenuates oxidative stress and diabetic cardiomyopathy (DCM), but the mechanism is unclear
Introduction
The aim of this study was to evaluate the contribution of xanthine oxidase (XO) to these phenomena using allopurinol, isolated or associated with
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Exercise Amaliorates Metabolic Disturbances and Oxidative Stress in Diabetic Cardiomyopathy: Possible Underlying Mechanisms, Exercise for Cardiovascular Disease Prevention and Treatment, 10