80mg/mL
Pregnancy Rating: C (US) Lactation: Oral maternal doses to 8mg daily is safe
4 mg
80
Dosage forms: INJ: 40 mg per mL, 80 mg per mL corticosteroid-responsive conditions [0
Applies to the following strengths: tebutate 20 mg/mL; sodium phosphate 20 mg/mL; 15 mg/5 mL; 5 mg; (as sodium phosphate) 5 mg/5 mL;
Adult Dosing
40 mg Act -O-Vial System (Single -Dose Vial)—Each mL (when mixed) contains methylprednisolone sodium succinate equivalent to 40 mg methylprednisolone; also Pediatric Use)
The pediatric dosage should not beless than 0
3 mg/kg/dose upto 30 mg
There are no clear guidelines on how frequently to give repeat dosing
1-2 mg/kg/day PO in single daily dose or divided q6-12hr; not to exceed 80 mg/day
Dosage forms: INJ: 20 mg per mL, 40 mg per mL, 80 mg per mL corticosteroid-responsive conditions [0
The treatment resulted in statistically significant reductions of generalized slow spike The initial dosage of MEDROL Tablets may vary from 4 mg to 48 mg of methylprednisolone per day depending on the specific disease entity being treated
Indication : Juvenile idiopathic arthritis; Connective tissue disorders – severe, life threatening; Vasculitis Infants and Children <12 years: Oral: 0
In pediatric patients, the initial dose range is 0
Dosage of methylprednisolone sodium succinate or methylprednisolone acetate is expressed in terms of methylprednisolone or methylprednisolone acetate, respectively
Patients should be given prednisolone PO or methylprednisolone IV 1 to 2 mg/kg/day or dexamethasone 0
, prednisone, methylprednisolone, prednisolone) Children: 1 mg per kg in two divided doses (maximum dosage is 60 mg per day) Adults: 40 to 80 mg per day in one or two Methylprednisolone: Usual dosing range, 0
2 mg/kg IM q12-24hr
Dosing should be individualized based on disease and patient response with less emphasis on strict adherence to age or body weight dosing: Initial dose: 0
OR
For children over the age of 11 that suffer from asthma, a daily dose of 7
Oral methylprednisolone is generally used as two divided doses due to its half-life, but there is no efficacy study for the use of pulse methylprednisolone therapy in two doses
2014 Jun;133 (6):E1518-24
IV methylprednisolone, oral prednisone and prednisolone are the corticosteroids most studied and cited in clinical guidelines; while this drug has been used, efficacy studies and comparative data are lacking